Thursday, September 17, 2026 at 8:15 PM EDT
Detroit Lions visited Buffalo Bills in Week 2 of the 2026 NFL season. They met at Highmark Stadium in Orchard Park, NY, with Prime Video carrying the broadcast. DET stand at 1-1, BUF at 2-0. The market had BUF -5.5 with a total of 54.5. It opened BUF -3. BUF won it 41-31.
Lines via DraftKings. Odds shown for reference only.
This week has been played, so its research is closed. The records stay on the board; the systems and trends behind them live in the Vault.