NFL · 2026

Buffalo Bills

Schedule, closing lines and results against the spread for the 2026 season.

2026 schedule

1. Sun, Sep 13Week 1@ Houston TexansW 36-31Line−1.5WTotal44.5O
2. Thu, Sep 17Week 2vs Detroit LionsW 41-31Line−5.5WTotal54.5O
3. Sun, Sep 27Week 3vs Los Angeles ChargersW 24-16Line−7WTotal50.5U
4. Sun, Oct 4Week 4vs New England PatriotsL 26-29Line−7LTotal49.5O
5. Mon, Oct 12Week 5@ Los Angeles RamsLiveLine+3.5Total55.5
6. Sun, Oct 18Week 6@ Las Vegas RaidersW 33-30Line−5.5LTotal54.5O
7. Sun, Nov 1Week 8vs Baltimore RavensW 36-10Line−3WTotal54.5U
8. Mon, Nov 9Week 9@ Minnesota VikingsLine−3.5Total46.5
9. Sun, Nov 15Week 10@ New York JetsLine−7Total46.5
10. Sun, Nov 22Week 11vs Miami DolphinsLine−11.5Total47.5
11. Thu, Nov 26Week 12vs Kansas City ChiefsLine−2.5Total50.5
12. Sun, Dec 6Week 13@ New England PatriotsLine+1.5Total48.5
13. Sun, Dec 13Week 14@ Green Bay PackersLine+1.5Total49.5
14. Sat, Dec 19Week 15vs Chicago BearsLine−3.5Total51.5
15. Fri, Dec 25Week 16@ Denver BroncosLine−1.5Total46.5
16. Sun, Jan 3Week 17@ Miami DolphinsLine−7.5Total47.5
17. Sun, Jan 10Week 18vs New York JetsLine−10Total43.5

Results are graded against the closing line, the last price posted before kickoff. Odds shown for reference only. If gambling stops being fun, call 1-800-GAMBLER.